Research Article

On the Use of Molecular Weight Cutoff Cassettes to Measure Dynamic Relaxivity of Novel Gadolinium Contrast Agents: Example Using Hyaluronic Acid Polymer Complexes in Phosphate-Buffered Saline

Figure 2

Hyaluronic acid repeat unit with amide bound diethylenediamine pentacetic acid. The Gd3+ ion is complexed with the bound DTPA ligand to yield the imaging agent, which is then coupled to HA via standard carbodiimide coupling methods.
808795.fig.002