White Matter Atrophy in Patients with Mesial Temporal Lobe Epilepsy: Voxel-Based Morphometry Analysis of T1- and T2-Weighted MR Images
Figure 1
Right side represents left side of the head. (a) A1 and A2: left MTLE; these images show the pattern of atrophy in coronal and axial slices, respectively, in a superposition of T1 and T2 acquisitions. The area colored in red represents areas of WM atrophy in T1-weighted images, and the area in blue represents WM atrophy in T2-weighted images. The intersection T1 and T2 is shown in purple. The figures show a bilateral pattern of WM atrophy, detected by both acquisitions, and a more widespread area in T1-weighted images, despite a considerable area of superposition. (b) B1 and B2: right MTLE; these images show the pattern of atrophy in coronal and axial slices, respectively, in a superposition of T1 and T2 acquisitions. The area colored in red represents WM atrophy in T1-weighted images, and the area in blue represents WM atrophy in T2-weighted images. The intersection T1 and T2 is shown in purple. The figures show a bilateral pattern of WM atrophy, detected by both acquisitions, and a more widespread area of WM atrophy in T1-weighted images, despite of a considerable area of superposition. (c) C1 and C2: left minus right MTLE groups: we made a subtraction between left and right MTLE patients. This subtraction evidentiates a pronounced WM atrophy in the ipsilateral (left) mesial area.
