Clinical Study

White Matter Atrophy in Patients with Mesial Temporal Lobe Epilepsy: Voxel-Based Morphometry Analysis of T1- and T2-Weighted MR Images

Table 3

Areas with WM atrophy on patients with left HA, from T2-weighted analysis.

Left atrophy T2
Number clusters (unc) , , (mm) Areas

7.320.000−22, −26, −16Left and right parahippocampal gyrus, thalamus, cingulate gyrus, corpus callosum, left and right hippocampus, insula, caudate
51784 6.39 0.000−33, −0, −31
6.24 0.000−2, −12, 12
5.77 0.0009, −39, −64 Left and right cerebellum
5105 5.00 0.00015, −57, −66
4.87 0.000−2, −50, −58
318 3.870.00066, −30, 9Left superior temporal and medial gyrus
3.670.00058, −38, 9
72 3.850.0009, −2, 75Right superior frontal gyrus
84 3.84 0.00026, 1, 71Right superior and middle frontal gyrus
583.710.00032, −75, 50Right parietal inferior and superior area
646 3.650.00015, −54, −33Right cerebellum
70 3.620.000−14, −65, −10Left lingual gyrus, left occipital lobe, and right cerebellum anterior lobe
224 3.580.000−33, −68, −61 Left cerebellum
2053.540.000−26, −80, −4 Left occipital lobe, left fusiform, and lingual gyrus
563.500.000−42, −2, 63Left middle frontal gyrus, left frontal lobe
78 3.290.00112, 4, −6Right pallidum, right lentiform nucleus, right putamen, and right caudate