Automated Determination of Arterial Input Function for Dynamic Susceptibility Contrast MRI from Regions around Arteries Using Independent Component Analysis

Table 2

rCBFs are calculated by the AIFs determined by the manual ROI (Manu-roi) and ICA-based ROI (weighted-ICA) method in gray and white matter regions. The paired -test is employed to test the difference between the manual and ICA-based method in the artery ( and ) and surrounding tissue ( and ) and between the artery and surrounding tissue in the ICA-based method in gray and white matter regions.

rCBF (mL/100 g/min)	Manu-roi			ICA-aw			ICA-sw
	#1 (36 y, m)	66.98	38.35	1.746	56.13	35.17	1.596	41.94	24.83	1.689
#2 (33 y, m)	54.22	28.22	1.921	54.25	30.78	1.762	40.83	21.98	1.857
#3 (32 y, m)	42.26	24.05	1.757	48.00	30.60	1.569	35.02	21.14	1.656
#4 (46 y, m)	45.79	29.57	1.549	40.33	30.16	1.337	38.70	24.55	1.576
#5 (35 y, f)	64.09	28.75	2.229	60.73	28.78	2.110	46.52	23.68	1.964
#6 (35 y, f)	49.08	21.95	2.236	48.09	22.13	2.173	46.75	21.17	2.208
#7 (38 y, f)	37.33	20.13	1.855	41.74	24.73	1.688	34.05	17.71	1.922
#8 (29 y, f)	69.27	32.20	2.151	66.52	34.73	1.915	45.10	21.55	2.093
Mean	53.63	27.90	1.931	51.97	29.64	1.769	41.11	22.08	1.871
Std	12.01	5.879	0.253	9.118	4.476	0.2839	4.935	2.309	0.221

GM = gray matter; WM = white matter; G/W = the ratio of gray matter and white matter.
Significantly (, paired -test) higher than in GM, WM, and G/W.
Significantly (, paired -test) higher than in GM, WM, and G/W.
Standard deviation.