Solid Indeterminate Pulmonary Nodules Less Than or Equal to 250 mm³: Application of the Updated Fleischner Society Guidelines in Clinical Practice

Table 4

Characteristics and histological features of the malignant nodules.

Nodule	Volume	Margins	Lobe location	Time interval 1st-last CT	Volume increment	VDT	Histology	Stage^§
	(mm^3)			(days)	(%)	(days)
1	135	Spiculated	Upper	316	71	407	ADC	IA2
2	55	Smooth	Upper	184	292	93	ADC	IA1
3	80	Lobulated	Upper	411	254	226	SCC	IA2
4	107	Lobulated	Lower	360	75	447	SCC	IA1
5	102	Smooth	Upper	165	175	113	SCC	IA1

At the baseline MDCT. ^§According to the 8th edition of the TNM staging.
VDT, volume doubling time; ADC, adenocarcinoma; SCC, squamous cell carcinoma.