Research Article
Predicting Molecular Subtypes of Breast Cancer with Mammography and Ultrasound Findings: Introduction of Sono-Mammometry Score
| | Imaging characteristics | Total (n = 313) | Luminal A (n = 62) | Luminal B-1 (Her-2−ve) (n = 71) | Luminal B-2 (Her-2+ve) (n = 47) | TNBC (n = 77) | Her-2 enrich (n = 56) | value |
| | Findings | | Negative | 7 (2.2) | 0 (0.0) | 2 (2.8) | 3 (6.4) | 1 (1.3) | 1 (1.8) | <0.01 | | Mass only | 197 (62.9) | 45 (72.6) | 46 (64.8) | 22 (46.8) | 64 (83.1) | 20 (35.7) | | Microcalcifications only | 10 (3.2) | 1 (1.6) | 1 (1.4) | 4 (8.5) | 0 (0.0) | 4 (7.1) | | Mass with microcalcifications | 92 (29.4) | 15 (24.2) | 19 (26.8) | 17 (36.2) | 12 (15.6) | 29 (51.8) | | Focal asymmetry | 7 (2.2) | 1 (1.6) | 3 (4.2) | 1 (2.1) | 0 (0.0) | 2 (3.6) |
| | Mass (n = 289) | | Margins | <0.01 | | Well circumscribed | 15 (4.8) | 1 (1.6) | 0 (0.0) | 0 (0.0) | 12 (15.6) | 2 (3.6) | | Non-well circumscribed | — | — | — | — | — | — | | Microlobulated | 40 (12.8) | 5 (8.1) | 1 (1.4) | 5 (10.6) | 28 (36.4) | 1 (1.8) | | Spiculated/obscured/indistinct | 234 (74.8) | 54 (87.1) | 64 (90.1) | 34 (72.3) | 36 (46.8) | 46 (82.1) |
| | Architectural distortion/trabecular thickening | | Yes | 226 (72.2) | 46 (74.2) | 59 (83.1) | 34 (72.3) | 39 (50.6) | 48 (85.7) | <0.01 | | No | 87 (27.8) | 16 (25.8) | 12 (16.9) | 13 (27.7) | 38 (49.4) | 8 (14.3) |
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TNBC: triple-negative breast cancer. |
