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Volume 2013, Article ID 787653, 7 pages
Clinical Study

Surgical Guides (Patient-Specific Instruments) for Pediatric Tibial Bone Sarcoma Resection and Allograft Reconstruction

1Computer-Assisted Robotic Surgery (CARS), Institut de Recherche Experimentale et Clinique (IREC), Tour Pasteur +4, Avenue Mounier 53, 1200 Brussels, Belgium
2Department of Orthopaedic Surgery, Cliniques Universitaires Saint-Luc, (Université Catholique de Louvain), Avenue Hippocrate 10, 1200 Brussels, Belgium

Received 21 October 2012; Revised 19 January 2013; Accepted 10 February 2013

Academic Editor: Hans Rechl

Copyright © 2013 Laura Bellanova et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


To achieve local control of malignant pediatric bone tumors and to provide satisfactory oncological results, adequate resection margins are mandatory. The local recurrence rate is directly related to inappropriate excision margins. The present study describes a method for decreasing the resection margin width and ensuring that the margins are adequate. This method was developed in the tibia, which is a common site for the most frequent primary bone sarcomas in children. Magnetic resonance imaging (MRI) and computerized tomography (CT) were used for preoperative planning to define the cutting planes for the tumors: each tumor was segmented on MRI, and the volume of the tumor was coregistered with CT. After preoperative planning, a surgical guide (patient-specific instrument) that was fitted to a unique position on the tibia was manufactured by rapid prototyping. A second instrument was manufactured to adjust the bone allograft to fit the resection gap accurately. Pathologic evaluation of the resected specimens showed tumor-free resection margins in all four cases. The technologies described in this paper may improve the surgical accuracy and patient safety in surgical oncology. In addition, these techniques may decrease operating time and allow for reconstruction with a well-matched allograft to obtain stable osteosynthesis.