Reactions of Subcutaneous Connective Tissue to Mineral Trioxide Aggregate, Biodentine®, and a Newly Developed BioACTIVE Base/Liner

Figure 1

Photomicrograph of H&E staining showing the subcutaneous tissue of the control (A), Biodentine® (B), ProRoot MTA (C), and ACTIVA BioACTİVE Base/Liner (D) after 7 days exposure. (a) Oedema, (b) inflammation, (c) fibrous capsule, and (d) calcification. (a) Mild oedema especially around the fibrous capsule areas was observed in all groups (H&E ×200). (b) Loose connective tissue and mild inflammation limited to the tube end, and giant cells were present in all groups (H&E ×200 and ×400). (c) Thin fibrous capsule formation was observed in all groups (H&E ×40). (d) Dystrophic calcification was observed around and inside the fibrous capsule in the Biodentine® (B), ProRoot MTA (C), and ACTIVA BioACTİVE Base/Liner (D) groups. No calcification was seen in the control group (H&E x 200).

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