Reactions of Subcutaneous Connective Tissue to Mineral Trioxide Aggregate, Biodentine®, and a Newly Developed BioACTIVE Base/Liner

Figure 3

Photomicrograph of H&E staining showing the subcutaneous tissue of the control (A), Biodentine® (B), ProRoot MTA (C), and ACTIVA BioACTİVE Base/Liner (D) after 60 days exposure. (a) Oedema, (b) inflammation, (c) fibrous capsule, and (d) calcification. (a) Oedema was present especially around the fibrous capsule in the ProRoot MTA (C) and ACTIVA BioACTİVE Base/Liner (D) groups (H&E ×40). (b) Loose connective tissue and mild inflammation were observed around the fibrous capsule in the Biodentine® (B), ProRoot MTA (C), and ACTIVA BioACTİVE Base/Liner (D) groups. No inflammation was present in the control group (H&E ×100 and ×200). (c) Fibrous capsule formation was present in all groups (H&E ×40). (d) Dystrophic calcification was observed around and inside the fibrous capsule in Biodentine® (B), ProRoot MTA (C), and ACTIVA BioACTİVE Base/Liner (D) groups. No calcification was seen in the control group (H&E ×200).

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