Clinical Application of Human Mesenchymal Stromal Cells for Bone Tissue Engineering
Figure 1
3D reconstruction of a skull and mandibular defect in trauma patients. Surgeons are often faced with patients having large defects in the bone which do not heal spontaneously. The gaping hole in the skull and the area highlighted in red in the mandible are examples of large-sized defects in real patients. Though autografts are the gold standard treatment for such patients, the amount of graft material required is often the limiting factor. Tissue regeneration using synthetic or natural scaffolds seeded with mesenchymal stem cells can be an alternative solution for such patients.
