Primitive Sca-1 Positive Bone Marrow HSC in Mouse Model of Aplastic Anemia: A Comparative Study through Flowcytometric Analysis and Scanning Electron Microscopy

Table 1

Peripheral blood hemogram showed a depressed hemoglobin level with uniformly reduced corpuscular counts, of which reticulocyte counts are significantly low ($\le 0.2$) in Aplastic groups compared with the normal range. The total WBC and Neutrophil counts were also found to be significantly low in the diseased group compared to the normal.

Parameters	Normal control groups (Mean $\pm$ SD)	Aplastic anemic groups (Mean $\pm$ SD)
Hemoglobin (g/dL)	$15.99\pm 0.26$	$9.08\pm 0.47$
WBC (x 10^3/$\mu$L)	$6.2\pm 1.28$	$2.7\pm 0.68$
RBC (x 10^6/$\mu$L)	$8.44\pm 0.32$	$3.8\pm 0.86$
Platelets (x 10^3/$\mu$L)	$432\pm 13.82$	$198\pm 14.36$
Reticulocyte(%)	$0.89\pm 0.15$	$0.18\pm 0.07$
Neutrophil(%)	$22.75\pm 2.21$	$7.35\pm 2.75$