Alteration in Marrow Stromal Microenvironment and Apoptosis Mechanisms Involved in Aplastic Anemia: An Animal Model to Study the Possible Disease Pathology
Figure 2
(a) The scanning electron micrographs of the normal bone marrow represented a well-organized compact cellular structures and intracellular association between the stem and stroma in the normal marrow microenvironment. (b) Scanning electron micrographs from the AA bone marrow acquainted an overall scanty and degenerative marrow with no such intertwined stem-stroma structure and distorted cellular components with frequent appearance of apoptic holes.
