Induction of Pluripotency in Adult Equine Fibroblasts without c-MYC
Figure 5
Differentiation potential of EiPS cells. (a) Embryoid body formation of EiPS cells grown in suspension medium in the absence of LIF. (b) Single EB, scale bar 500 μM. (c) Gene expression profile of EiPS cells following differentiation of embryoid body. (d) Histology of differentiated tissues found in the hind leg muscle of SCID mice following injection of EiPS cells included (i) endodermal differentiation, (ii) mesodermal differentiation, (iii) ectodermal (neuroblastic) differentiation, scale bar 100 μM.
