Research Article

Assessment of Hereditary Retinal Degeneration in the English Springer Spaniel Dog and Disease Relationship to an RPGRIP1 Mutation

Figure 4

(a) Light microscopy (LM) of the inferior nontapetal retina of the 9-year-old ESS dog. Severe thinning of the entire retina is seen with complete degeneration of photoreceptor cells and inner retinal degeneration, disorganization, and gliosis. (b) LM of superior tapetal retina. A variation in retinal thickness is observed and some areas with a single row of photoreceptor nuclei that are still present. Toluidine blue staining; ×40.
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(a)
685901.fig.004b
(b)