Research Article
In Vivo Healing of Meniscal Lacerations Using Bone Marrow-Derived Mesenchymal Stem Cells and Fibrin Glue
Table 1
Explanation of grading rubric used in the current study and the coding used for the results.
| Category/score | 0 | 1 | 2 | 3 | Gross observations | | | | |
| Adherent vessels | Vessels on 1 side only | Vessels on 2 sides | Multiple vessels on multiple sides | | Tissue adhesion | No Tissue Adhesion | Areas of external tissue adhered | | | Bond | No bond | Flexible bond | Firm attachment | |
| H&E section observations | | | | |
| Cellular in-growth | Acellular along cut edge | Incomplete cellular repopulation | 50% in-growth | Complete repopulation along cut edge | Predominant cell type | | Small round cells (fibrocytes) | Larger less dense cells (inflammatory origin) | 50-50 dispersed | Fiber organization | Disorganized | 50% parallel fibers | Greater than 70% organization | | Fibrinous tissue between sections | Large amounts of fibrous tissue present | No large fibrous tissue sections present | | |
| SOFG section observations | | | | |
| SOFG % positive staining | None | Less than 50% | More than 50% | Near 100% | Thickness of repair tissue | | Thin | Medium | Thick | Cell repopulation | Rare | Moderate | Frequent | | Total bond distance | 25% | 25–50% | 50–75% | 75–100% |
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