Research Article

In Vivo Healing of Meniscal Lacerations Using Bone Marrow-Derived Mesenchymal Stem Cells and Fibrin Glue

Table 1

Explanation of grading rubric used in the current study and the coding used for the results.

Category/score0123
Gross observations

 Adherent vesselsVessels on 1 side onlyVessels on 2 sidesMultiple vessels on multiple sides
 Tissue adhesionNo Tissue AdhesionAreas of external tissue adhered
 BondNo bondFlexible bondFirm attachment

H&E section observations

 Cellular in-growthAcellular along cut edgeIncomplete cellular repopulation50% in-growthComplete repopulation along cut edge
 Predominant cell typeSmall round cells (fibrocytes)Larger less dense cells (inflammatory origin)50-50 dispersed
 Fiber organizationDisorganized50% parallel fibersGreater than 70% organization
 Fibrinous tissue between sectionsLarge amounts of fibrous tissue presentNo large fibrous tissue sections present

SOFG section observations

 SOFG % positive stainingNoneLess than 50%More than 50%Near 100%
 Thickness of repair tissueThinMediumThick
 Cell repopulationRareModerateFrequent
 Total bond distance25%25–50%50–75%75–100%