Expression of SIRT1 and DBC1 in Developing and Adult Retinas
Figure 2
SIRT1 expression in mouse eyes. (a) Postnatal day 1 (P1) mouse eye (50x). (b) Higher magnification of (a) (640x). Ganglion cells and nerve fibre layer stained positive. (c) Inner and outer plexiform layers stained positive while the inner and outer nuclear layers are negative for SIRT1 in this specimen (P244 mouse eye; 400x). (d) SIRT1 staining in adult mouse retina (green). Insert highlights cytoplasmic staining in ONL. (e) SYTO 60 nuclear stain of retinal cell nuclei (red). (f) Composite image of (d) and (e) showing predominant cytoplasmic localization of SIRT1 in this section.
