Stem Cells International / 2012 / Article / Fig 4

Clinical Study

Bilateral Transplantation of Allogenic Adult Human Bone Marrow-Derived Mesenchymal Stem Cells into the Subventricular Zone of Parkinson’s Disease: A Pilot Clinical Study

Figure 4

Shows T2 FLAIR axial images. (a) Depicts bilateral asymmetric multifocal hyperintensities involving pontine base periventricular and deep white matter suggestive of small-vessel ischemia. Diffuse brain atrophy is also seen with mineralization below globus pallidus and substantia nigra indicative of PD. There is no significant difference noted between the baseline and follow-up MRI. (b) Depicts moderate brain atrophy with bilateral putaminal rim sign seen. Small-vessel ischemic changes are seen in the bilateral periventricular and deep white matter. Mineralization of bilateral lentiform nuclei, dentate nuclei, and substantia nigra visualized is suggestive of MSA-P or PD plus syndrome. There was no significant difference noted between the baseline and follow-up MRI.
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(a)
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(b)

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