Review Article

Stem Cells as In Vitro Model of Parkinson's Disease

Table 1

Examples of in vitro models to study Parkinson’s disease derived from patient iPSC.

GeneGenetic diseaseGenetic alterationReferences

SNCA Autosomal dominantTriplication of α-synuclein locus[31]
G209A mutation[43]
LRRK2Autosomal dominantp.G2019S mutation[30]
PINK1Autosomal recessivep.Q456X and p.V170G mutation[45]
Idiopathic conditionIdiopathic[32, 42]