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Stem Cells International
Volume 2014 (2014), Article ID 316214, 19 pages
http://dx.doi.org/10.1155/2014/316214
Research Article

Reducing TRPC1 Expression through Liposome-Mediated siRNA Delivery Markedly Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension in a Murine Model

1Department of Emergency Medicine, E-Da Hospital, I-Shou University College of Medicine, Kaohsiung 82445, Taiwan
2Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan
3Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan
4Basic Science, Nursing Department, Meiho Institute of Technology, Pingtung 91202, Taiwan
5Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung 80424, Taiwan
6Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan
7Institute of Shock Wave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan

Received 7 July 2014; Revised 15 September 2014; Accepted 19 September 2014; Published 18 December 2014

Academic Editor: Gary E. Lyons

Copyright © 2014 Cheuk-Kwan Sun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Cheuk-Kwan Sun, Yen-Yi Zhen, Hung-I Lu, et al., “Reducing TRPC1 Expression through Liposome-Mediated siRNA Delivery Markedly Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension in a Murine Model,” Stem Cells International, vol. 2014, Article ID 316214, 19 pages, 2014. doi:10.1155/2014/316214