Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos

Figure 3

Generation of mouse chimeras by injection of ESCs into 8-cell embryos. Blastocysts developed from ES cell injection ((a) bright field; (b) GFP fluorescence). The white arrow shows that ESCs were aggregated into the ICM of blastocysts. Chimeric mice generated by injecting ESCs into 8-cell embryos (c). The black arrow shows the full agouti-colored chimeric mouse.

(a)

(b)

(c)