Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos

Table 2

Generation of chimeric mice with ESCs.

Method	Number of embryos; transferred	Number of; recipients	Number of pregnant; recipients (%)	Number of; pups	Number of chimeras (%)
					Total	Full colored
8-cell coculture	312	14	11 (78.6)^a	86	25 (29.1)^ab	3 (12.0)^a
8-cell injection	365	17	14 (82.4)^a	127	23 (18.1)^a	1 (4.3)^a
Blastocyst injection	129	6	6 (100)^a	73	28 (38.4)^b	0 (0.0)^a
Total	806	37	31 (83.8)	286	76 (26.6)	4 (1.4)

Values with different superscripts within the same column are significantly different ().