Bone Marrow-Derived Multipotent Stromal Cells Attenuate Inflammation in Obliterative Airway Disease in Mouse Tracheal Allografts
Figure 2
MSCs suppress neutrophil infiltration in the allografts. To assess neutrophil infiltration, donor tracheas from each treatment group were explanted 2 days (PBS, ; MSC, ) or 1 week (PBS, ; MSC, ) after transplantation. (a) Representative tracheal sections stained with anti-Ly6C/6G antibodies (dark brown spots, 200x original magnification). (b) The total number of neutrophils per section was counted, and the mean values of 2 days and 1 week after transplantation in the MSC/IV + T-treated group were compared to the respective PBS control group. Significantly less neutrophils were found in the MSC/IV + T-treated group (; ). All error bars in (b) indicate SEM.
