Review Article

Concise Review: Mesenchymal Stem Cells Ameliorate Tissue Injury via Secretion of Tumor Necrosis Factor-α Stimulated Protein/Gene 6

Figure 2

Structure of human TSG-6. TSG-6 is a ~35 kDa secreted protein composed mainly of contiguous link and CUB modules. On the basis of our structural and modelling studies, these can be defined as residues 37–128 and 129–250 in the preprotein.