Whole Genome Expression Profiling and Signal Pathway Screening of MSCs in Ankylosing Spondylitis

Table 3

GO analysis of differentially expressed genes associated with the cellular location and molecular function.

Category	GO ID	Term	Count of genes	Percent of count of genes	Fold enrichment	value
GOTERM_CC	GO:0000307	Cyclin-dependent protein kinase Holoenzyme complex	4	0.92	12.35	0.00022
GOTERM_CC	GO:0005576	Extracellular region	82	18.76	1.52	0.00006
GOTERM_CC	GO:0005615	Extracellular space	29	6.64	1.6	0.00908
GOTERM_CC	GO:0005881	Cytoplasmic microtubule	3	0.69	6.95	0.00842
GOTERM_CC	GO:0016324	Apical plasma membrane	10	2.29	2.39	0.00945
GOTERM_CC	GO:0043005	Neuron projection	18	4.12	2	0.00423
GOTERM_CC	GO:0044421	Extracellular region part	41	9.38	1.61	0.00181
GOTERM_CC	GO:0045095	Keratin filament	8	1.83	3.29	0.00297
GOTERM_MF	GO:0000287	Magnesium ion binding	22	5.2	1.73	0.009
GOTERM_MF	GO:0004725	Protein tyrosine phosphatase activity	8	1.89	2.86	0.007
GOTERM_MF	GO:0005057	Receptor signaling protein activity	11	2.6	2.51	0.0047
GOTERM_MF	GO:0005102	Receptor binding	37	8.75	1.55	0.0055
GOTERM_MF	GO:0005104	Fibroblast growth factor receptor binding	4	0.95	6.95	0.0023
GOTERM_MF	GO:0005201	Extracellular matrix structural constituent	7	1.65	3.04	0.0082
GOTERM_MF	GO:0005262	Calcium channel activity	7	1.65	3.32	0.0051
GOTERM_MF	GO:0008083	Growth factor activity	12	2.84	2.72	0.0016
GOTERM_MF	GO:0008138	Protein tyrosine/serine/threonine phosphatase activity	6	1.42	4.86	0.0014
GOTERM_MF	GO:0008168	Methyltransferase activity	11	2.6	2.27	0.0097
GOTERM_MF	GO:0008276	Protein methyltransferase activity	6	1.42	3.77	0.005
GOTERM_MF	GO:0042054	Histone methyltransferase activity	5	1.18	4.05	0.0075