Research Article

Whole Genome Expression Profiling and Signal Pathway Screening of MSCs in Ankylosing Spondylitis

Table 4

Ankylosing spondylitis KEGG pathway analysis result.

Group comparedKEGG pathway ID and nameCount of genesPercent of count of genesGene name value

Normal environmentHsa04010: MAPK signaling pathway20.30%CACNA2D3, PPM1B0.12000
Hsa04620: toll-like receptor signaling pathway10.15%TLR60.20000

Inflammatory environmentHsa04010: MAPK signaling pathway140.79%GNA12, DUSP1, MAPK11, RAC1, MRAS, ELK1, ATF4, MAPK3, CDC25B, STMN1, MAX, TGFBR2, CACNB3, FGF8, and RASA20.00000
Hsa04620: toll-like receptor signaling pathway80.45%RAC1, TRAF3, MAPK3, IFNAR1, TICAM1, IL6, MAPK11, and IFNA10.00002