Neural Differentiation of Human Pluripotent Stem Cells for Nontherapeutic Applications: Toxicology, Pharmacology, and In Vitro Disease Modeling

Table 2

Examples of drug leads screened with hPSCs-derived neuronal lineages.

Drug lead	Disease model	Key references
Sulindac sulfide; Compound E; -secretase inhibitor IV	Alzheimer’s disease	Ebert et al. [74]
Compound W	Alzheimer’s disease	Yagi et al. [75]
Loxapine	Schizophrenia	Brennand et al. [73]
Valproic acid	Spinal muscular atrophy	Ebert et al. [74]