MicroRNA Regulation of Brain Tumour Initiating Cells in Central Nervous System Tumours

Table 3

miRNAs regulating BTICs in other CNS tumours.

Tumour	miRNA	Target/putative target	Expression level	References
Pituitary adenoma	miRNA-16-1	BCL1	Downregulated	[134]
	Let-7	HMGA2	Downregulated	[156]
	miR-128	Bmi1	Downregulated	[168–170]
	miR-143	ERK5	Downregulated	[169, 193]
	miR-126	PTTG1	Downregulated	[178]
	miR-381	PTTG1	Downregulated	[178]
	miR-132, miR-136, miR-127, miR-129, miR-203, miR-134, miR-127, miR-141, miR-145	N/A	Downregulated	[168, 176, 194]
	miRNA-128a	Wee1	Upregulated	[169]
	miRNA-155	Wee1	Upregulated	[169]
	miRNA-516-3p	Wee1	Upregulated	[168, 169]
	miR-26b	PTEN	Upregulated	[168–170]
	miR-26a	PKCd	Upregulated	[195]
	miR-212	DEDD	Upregulated	[176, 177]
	miR-150, miR-152, miR-191, miR-192 miR-23a, miR-23b, miR-24-2, miR-137	N/A	Upregulated	[168, 176, 194]
Craniopharyngioma	miR-141, miR-16, miR-449, miR-145, let-7a, miR-143, miR-23b, miR-15a, miR-24-2	N/A	Downregulated	[134]
	miR-150	N/A	Upregulated	[134]
AT/RT	let-7b	HMGA2	Downregulated	[99, 154]
	let-7a3	HMGA2	Downregulated	[99, 154]
	miR-140, miR-139, miR-153, miR-376b	N/A	Downregulated	[99, 154]
	miR-520b, miR-629, miR-221, miR-498, miR-373	N/A	Upregulated	[99, 154]
Pilocytic astrocytoma	miR-93, miR-135a, miR-129, miR-135b, miR-106b, miR-181b-5p	N/A	Downregulated	[99, 180]
	miR-432, miR-29a, miR-138, miR-299-5p, miR-34a	N/A	Upregulated	[99]
Ependymoma	miR-485-5p, miR-383, miR-139, miR-323, miR-433, miR-137, miR-138, miR-124a, miR-181d, miR-193b	N/A	Downregulated	[99, 143]
	miR-34a, miR-135a, miR-17-5p, miR-10a, miR-19a, miR-19b, miR-20a, miR-21, miR-32, miR-34c, miR-34b, miR-200b, miR-200a, miR-483miR-106b, miR-130a, miR-135a, miR-142-3, miR-193, miR-210, miR-301, miR-449b, miR-502, miR-518b, miR-551b, miR-565, miR-591, miR-594, miR-601	N/A	Upregulated	[99]