Research Article

Dynamic Support Culture of Murine Skeletal Muscle-Derived Stem Cells Improves Their Cardiogenic Potential In Vitro

Figure 5

Electrophysiological analyses of MDSC-derived cells. (a) Representative action potential traces of initial cell population (ISH0) and after applying different cell culture conditions for 12 days (I12, S12, and H12) as measured by a whole-cell patch-clamp in current-clamp mode. (b) Voltage clamp measurements for recording of the pacemaker current . The applied voltage protocol is shown above the traces, which are representative for cells which do not express (upper trace) and which express small (lower trace) currents.