Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer

<div>(a) Correlation of OPN mRNA overexpression with SOX2 mRNA overexpression in CRC patients. (b) Correlation of OPN protein expression with SOX2 protein expression in CRC tissues of 11 patients. (c) Representative images showing correlation of OPN and SOX2 protein expression in CRC tissues (621T: OPN high/SOX2 high; 767T: OPN low/SOX2 low). Negative/weak staining of OPN and SOX2 were detected in most adjacent normal tissues (N).</div>

Stem Cells International

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Figure 3: Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer 

Figure 3 | Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer 