Review Article
Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells
Table 1
Summary of references for natural materials in combination with hydroxyapatite.
| Source of stem cells | Material used | Results | Study/reference |
| hMSCs | Collagen/fibronectin/HA | Cells are viable on the scaffold | Antebi et al. 2013/[12] | BMSCs and DPSCs | Fibronectin/collagen/albumin coating for HA versus allographs | ↑ cell attachment for allographs coated with albumin | Weszl et al. 2012/[13] | BMSCs, PDL fibroblasts, and HBCs | Gelatin/HA | ↑ ALP activity for moderate HA levels | Rungsiyanont et al. 2012/[14] | WJ-MSCs | HA/gellan gum/gelatin | Cells are viable on the scaffold | Barbani et al. 2012/[15] | BMSCs | CS/HA | ↑ osteocalcin expression/staining, ↑ ALP expression/staining, ↑ Col1αI expression, ↑ Runx2 expression | Kim et al. 2013/[16] | BMSCs | CS/hyaluronic acid/nHA | ↑ ALP activity | Chen et al. 2012/[17] | BMSCs | CS/fibronectin/vitronectin/nHA | ↑ calcium deposition, ↑ collagen content, ↑ total protein synthesis | Wang et al. 2014/[18] | hMSCs | CS/PgA/nanoclay | ↑ ARZ staining, ↑ ALP activity | Ambre et al. 2013/[19] | BMSs | Silk/HA | ↑ collagen I staining, ↑ bone sialoprotein staining, ↑ osteocalcin staining, ↑ calcium deposition | Bhumiratana et al. 2011/[20] |
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