Review Article

Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells

Table 2

Summary of references for synthetic materials in combination with hydroxyapatite.

Source of stem cellsMaterial usedResultsStudy/reference

BMSCsPCL/nHA↑ ALP staining, ↑ Alizarin red staining, ↑ rhBMP-2Xia et al. 2013/[21]
Primary human osteoblasts/ASCsPCL/BCP-nHA↑ Runx2 expression, ↑ osteopontin expression, ↑ bone sialoprotein expression, ↑ osteocalcin expressionLu et al. 2012/[22]
(WJ) MSCsPHB/gelatin/nHA↑ ALP activity Ramier et al. 2014/[23]
BMSCsPVA/BCPFavorable morphological characteristicsNie et al. 2012/[24]
BMSCsPLGA/nHA↑ ALP activity, ↑ Alizarin red staining, ↑ osteopontin staining, ↑ osteocalcin staining Lv et al. 2013/[25]
ASCsTris(PETA-co-TMPTMP)/HA ↓ Almar blue stainingGarber et al. 2013/[26]
BMSCsPOC/HA↑ ALP activity Chung et al. 2012/[27]