Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells

Table 4

Summary of references for recent advances in skeletal disease/injury treatment.

Source of stem cells	Material used	Results	Study/reference
hUCMSCs	CS/PLGA/nHA	↑ osteocalcin, ↑ ALP activity, ↑ osteoid tissue formation	Wang et al. 2014/[34]
hMSC	HA/Beta-TCP with hPL coating	↑ osteogenic regeneration, ↑ angiogenesis	Leotot et al. 2013/[29]
hMSC	HA/Beta-TCP/hPL/HA	↑ mineralization	Chen et al. 2012/[30]
BMSCs	CHACC	↑ ALP activity, ↑ mature collagen deposition, and bone tissue formation	Fu et al. 2013/[35]
BMSCs	Collagen/platelet gel	Bone formation was visible after ten weeks	Stanko et al. 2013/[36]
BMSCs	TCP/PDGF/HA	Healing without complications	Behnia et al. 2012/[37]
htMSC	Bioceramic	↑ neobone formation, ↓ inflammation	Jazedje et al. 2012/[38]
hUCMSCs	Collagen/Sr/HA	↑ bone density, ↑ bone formation, ↑ ECM formation, ↑ Beta-catenin	Yang et al. 2011/[39]
ASCs	HA	↑ RUNX2 expression, ↑ osteopontin expression, ↑ osteocalcin expression, ↑ expression staining	Gardin et al. 2012/[28]
BMSCs	Autograph, allograph, PCL/HA	↑ elastic stiffness, ↑ viscous stiffness, ↑ callous formation	Amorosa et al. 2013/[40]
BMSCs	HA	↑ osteoinductivity, ↓ inflammation	Vaněček et al. 2013/[41]