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Figure 5: Cumulative levels of inflammatory cytokines and chemokines are significantly increased in 56Fe-IR conditioned medium. Graphic representation of IR-induced increase in the cumulative concentration (pg/mL) of cytokines, chemokines, and growth factors in CM from 15 cGy 56Fe-IR BM-EPCs in vitro at 2, 5 and 24 hours post-IR for (a) IL-1α, (b) IL-1β, (c) G-CSF, (d) GM-CSF, (e) MCP-1, (f) MIP-1α, (g) SCF, and (h) Rantes. Graphs represent mean ± SEM of the pooled data from 3 independent biological samples/experiments. Statistical significance was assigned when .