Review Article
Trophic Factors from Tissue Stem Cells for Renal Regeneration
Table 2
Summary of the adult kidney stem cells.
| Factor | Trophic effect |
| HGF | Cell proliferation, anti-inflammation, antifibrosis | EGF | Mitogenesis (renal proximal tubules), anabolism | IGF-1 | Mitogenesis (renal proximal tubules) | bFGF | Antiapoptosis, epithelial condensation, WT-1 upregulation, cell proliferation, MSC differentiation | VEGF | Cell proliferation, matrix remodeling, monocyte chemotaxis, adhesion protein upregulation | BMP-7 | Antifibrosis, anti-inflammation, antiapoptosis | PGE2 | Anti-inflammation | TGF-b | Anti-inflammation | MVs | Cell proliferation, antiapoptosis, dedifferentiation (renal mature cells) | microRNAs | Kidney development, homeostasis, and renal disease |
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