Human Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option for Tooth Regeneration

Figure 4

hTDM induces hUCMSCs into odontoblast-like cells in vitro. (a) Detection of DSP and DMP-1 in hTDM-induced hUCMSCs and normal cultured hUCMSCs without hTDM by immunocytochemistry. (b) Western blotting showed that hTDM-induced hUCMSCs and pulp tissue expressed DSP and DMP-1, while uninduced hUCMSCs did not express these proteins. (c) and (d) Relative mRNA levels of DMP-1 and DSPP were determined by quantitative PCR.

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