Human Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option for Tooth Regeneration

Figure 5

hTDM induces hUCMSCs into odontoblast-like cells in vivo. (a) HE staining of hTDM-hUCMSC composites after subcutaneous implantation into nude mice for 8 weeks. (b) Masson’s tricolor staining of hTDM-hUCMSC composites after subcutaneous implantation into nude mice for 8 weeks. (c) Newly formed calcification and adhesive cells on hTDM were positive for DSP and DMP-1 as detected by immunohistochemistry.

(a)

(b)

(c)