Stem Cells International

Research Article

Characterization of Human Knee and Chin Adipose-Derived Stromal Cells

Table 1

TOP50 of the down- and upregulated genes between knee and chin adipose tissue depots from the large scale transcriptomic experiment.
Gene symbolGene titleKnee versus chin FDR Fold change
ACTA1Actin, alpha 1, skeletal muscle0,0006−69,62
MYH2Myosin, heavy chain 2, skeletal muscle, adult0,0004−65,45
KBTBD10Kelch repeat and BTB (POZ) domain containing 100,0016−62,65
MYL1Myosin, light chain 1, alkali; skeletal, fast0,0026−31,4
CKMCreatine kinase, muscle0,0026−29,47
MYBPC1Myosin binding protein C, slow type0,0027−28,89
MBMyoglobin0,0025−25,84
MYL2Myosin, light chain 2, regulatory, cardiac, slow0,0029−24,41
SLNSarcolipin0,0052−22,39
CSRP3Cysteine and glycine-rich protein 3 (cardiac LIM protein)0,0034−18,46
NEBNebulin0,0037−17,84
MYOTMyotilin0,0046−16,77
TTNTitin0,0069−16,52
SMPXSmall muscle protein, X-linked0,0094−14,54
COL6A6Collagen, type VI, alpha 60,0004−14,47
KBTBD10Kelch repeat and BTB (POZ) domain containing 100,0093−14,24
TNNC2Troponin C type 2 (fast)0,0043−13,86
TNNI2Troponin I type 2 (skeletal, fast)0,0076−13,15
TNNC1Troponin C type 1 (slow)0,0053−12,35
TNNT1Troponin T type 1 (skeletal, slow)0,0051−12,08
XIRP2Xin actin-binding repeat containing 20,0086−11,91
TPM1Tropomyosin 1 (alpha)0,0092−11,73
ENO3Enolase 3 (beta, muscle)0,0059−11,71
PDLIM5PDZ and LIM domain 50,0085−10,49
ASB5Ankyrin repeat and SOCS box-containing 50,0142−10,38
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle0,0092−9,51
CADM2Cell adhesion molecule 25,51E − 05−9,22
MYH6 Myosin, heavy chain 6, cardiac muscle, alpha///myosin0,0105−8,65
CA3Carbonic anhydrase III, muscle specific0,0006−8,27
MYBPC2Myosin binding protein C, fast type0,0097−8,06
MYOZ1Myozenin 10,012−7,9
ACTN2Actinin, alpha 20,0155−7,86
TRDNTriadin0,0075−7,71
CADM2Cell adhesion molecule 20,0003−6,45
CYR61Cysteine-rich, angiogenic inducer, 610,0002−6,29
PAX3Paired box 30,0001−6,26
TTNTitin0,0317−6,11
CADM2Cell adhesion molecule 20,0003−5,98
AMPD1Adenosine monophosphate deaminase 10,0243−5,97
LDB3LIM domain binding 30,0143−5,96
LMOD2Leiomodin 2 (cardiac)0,0218−5,94
TPM3Tropomyosin 30,0139−5,9
APOBEC2Apolipoprotein B mRNA editing enzyme0,0126−5,8
C8orf22Chromosome 8 open reading frame 220,008−5,79
RBM24RNA binding motif protein 240,0006−5,74
TTNTitin0,0171−5,62
PDLIM5PDZ and LIM domain 50,0325−5,57
CYR61Cysteine-rich, angiogenic inducer, 610,0002−5,45
CMYA5Cardiomyopathy associated 50,0152−5,31
PKIAProtein kinase (cAMP-dependent, catalytic) inhibitor alpha0,0038−5,31
PCDH7Protocadherin 70,0008−5,23
HSPB3Heat shock 27kDa protein 30,0235−5,19
PPBPProplatelet basic protein (chemokine (C-X-C motif) ligand 7)0,0153−5,14
MYH1Myosin, heavy chain 1, skeletal muscle, adult0,0276−5,11
NRAPNebulin-related anchoring protein0,0129−5,08
POPDC3Popeye domain containing 30,0033−5,03
MYOZ2Myozenin 20,0209−4,99
HOXA10Homeobox A101,40E − 0937,88
HOXA9Homeobox A99,16E − 0823,43
HOXA9Homeobox A98,09E − 0713,38
HOXC6Homeobox C61,93E − 079,92
TNCTenascin C0,00058,26
HOXC10Homeobox C103,47E − 067,8
IGH@///IGHG1///Immunoglobulin heavy locus0,00217,59
IGJImmunoglobulin J polypeptide0,00837,41
HOXA10Homeobox A103,47E − 067,37
CHI3L1Chitinase 3-like 1 (cartilage glycoprotein-39)0,00087,09
SAA1///SAA2Serum amyloid A1///serum amyloid A20,00047,04
HOXA3Homeobox A35,60E − 056,88
HOXC9Homeobox C91,32E − 065,87
CYAT1///IGLV1-44Cyclosporin A transporter 1/0,00765,83
ASPNAsporin1,32E − 065,76
HOXA5Homeobox A59,27E − 055,28
ASPNAsporin4,94E − 065,2
CHI3L1Chitinase 3-like 1 (cartilage glycoprotein-39)0,00214,82
SAA1///SAA2Serum amyloid A1///serum amyloid A20,00114,75
ATP8B4ATPase, class I, type 8B, member 42,99E − 064,61
IGL@Immunoglobulin lambda locus0,00584,6
CSN1S1Casein alpha s10,01434,04
CYAT1///IGLV1-44Cyclosporin A transporter 10,0083,96
PRG4Proteoglycan 40,0013,95
IGH@///IGHA1 Immunoglobulin heavy locus0,01723,75
HOXA7Homeobox A75,44E − 053,69
HOXB7Homeobox B72,43E − 053,63
IGLV1-44Immunoglobulin lambda variable 1-440,0133,6
ALDH1A3Aldehyde dehydrogenase 1 family, member A30,00023,54
FGFBP2Fibroblast growth factor binding protein 20,00133,54
ZIC1Zic family member 1 (odd-paired homolog, Drosophila)0,00543,5
CPCeruloplasmin (ferroxidase)0,00033,43
IGK@///IGKCImmunoglobulin kappa locus t0,01323,39
IGK@///IGKCImmunoglobulin kappa locus///immunoglobulin kappa constant0,0123,37
ISM1Isthmin 1 homolog (zebrafish)0,00063,36
PHLDA2Pleckstrin homology-like domain, family A, member 20,00113,34
NPY1RNeuropeptide Y receptor Y10,00173,31
EVI2AEcotropic viral integration site 2A0,00143,29
HOXB7Homeobox B72,86E − 053,29
FCER1AFc fragment of IgE, high affinity I, receptor for alpha polypeptide0,00123,28
MSR1Macrophage scavenger receptor 10,00023,23
CNTN4Contactin 40,00213,23
IGKCImmunoglobulin kappa constant0,013,21
PLA2G7Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)0,00763,21
MS4A7Membrane-spanning 4 domains, subfamily A, member 70,00043,19
RNASE6Ribonuclease, RNase A family, k60,00033,18
IGK@///IGKCImmunoglobulin kappa locus///immunoglobulin kappa constant0,01843,18
CRISPLD1Cysteine-rich secretory protein LCCL domain containing 10,00093,17
CPCeruloplasmin (ferroxidase)0,00043,17
CHI3L2Chitinase 3-like 20,00333,12
CLEC7AC-type lectin domain family 7, member A0,02053,1
LYZLysozyme0,01233,07
BGNBiglycan0,00053,06
LYZLysozyme0,00832,94
MARCH1Membrane-associated ring finger (C3HC4) 10,00022,92
IGK@///IGKC///LOC100291464Immunoglobulin kappa locus///immunoglobulin kappa constant///similar to hCG266590,01722,91
SAMSN1SAM domain, SH3 domain, and nuclear localization signals 10,00132,91
ANKDD1AAnkyrin repeat and death domain containing 1A0,00062,88