Concise Review: Are Stimulated Somatic Cells Truly Reprogrammed into an ES/iPS-Like Pluripotent State? Better Understanding by Ischemia-Induced Multipotent Stem Cells in a Mouse Model of Cerebral Infarction

Figure 1

iSCs were isolated from ischemic areas and formed cells clusters (a). iSCs as well as control ES cells expressed c-myc, Klf4, Sox2, and Nanog. However, Oct4 was not observed even after > 35 cycles of PCR amplification. The cycle number of PCR amplification is shown in the circles (b).

(a)

(b)