Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial Infarction

Figure 5

The in vitro angiogenic properties of -derived exosomes. (a) Induction of tube formation by MSC-derived exosomes in HUVEC. (b) Quantitative data of total branch points in various groups. (c) VEGF expression in various groups was analyzed by qPCR. versus . All values expressed as mean ± SEM, for each group. HUVEC + , HUVEC treated with -derived exosomes; HUVEC + , HUVEC treated with -derived exosomes; HUVEC + + LY, HUVEC + treated with LY294002 (a PI3K inhibitor); HUVEC + + LY, HUVEC + treated with LY294002; HUVEC + , HUVEC treated with -derived exosomes.

(a)

(b)

(c)