Research Article
Bone Marrow-Derived Multipotent Stromal Cells Promote Myocardial Fibrosis and Reverse Remodeling of the Left Ventricle
Table 1
The dynamics of cardiac function variables before and after the transplantation, mean ± SEM.
| | Before infusion | 14 days | 30 days | | Saline | AutoMSCs | AlloMSCs | Saline | AutoMSCs | AlloMSCs | Saline | AutoMSCs | AlloMSCs |
| Tolerance, min | 20 ± 2 | 17 ± 1 | 17 ± 1 | | | 2 | 16 ± 3 | | 2 | HR, hb/min | 199 ± 17 | 214 ± 10 | 212 ± 17 | 231 ± 8 | 224 ± 20 | 233 ± 14 | 216 ± 11 | 237 ± 10 | 198 ± 22 | Average BP, mm Hg | 77 ± 4 | 88 ± 6 | 82 ± 4 | 79 ± 2 | 83 ± 3 | 78 ± 2 | | 84 ± 2 | 76 ± 2 | LV BP max., mm Hg | 84 ± 5 | 82 ± 7 | | 110 ± 3 | 108 ± 5 | | | | | +/ | 4128 ± 798 | 3725 ± 211 | 3913 ± 420 | 7112 ± 624 | | 5824 ± 72 | 7781 ± 364 | | | −/ | 2396 ± 438 | 2220 ± 215 | 2330 ± 261 | | | | | | |
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< 0.05 as compared to initial values. < 0.05 as compared to the controls. < 0.05 as compared to p/t day 14.
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