Research Article

Bone Marrow-Derived Multipotent Stromal Cells Promote Myocardial Fibrosis and Reverse Remodeling of the Left Ventricle

Table 1

The dynamics of cardiac function variables before and after the transplantation, mean ± SEM.

Before infusion14 days30 days
Saline AutoMSCsAlloMSCsSalineAutoMSCsAlloMSCsSalineAutoMSCsAlloMSCs

Tolerance, min20 ± 217 ± 117 ± 1216 ± 32
HR, hb/min199 ± 17214 ± 10212 ± 17231 ± 8224 ± 20233 ± 14216 ± 11237 ± 10198 ± 22
Average BP,
mm Hg
77 ± 488 ± 682 ± 479 ± 283 ± 378 ± 284 ± 276 ± 2
LV BP max.,
mm Hg
84 ± 582 ± 7110 ± 3108 ± 5
+/4128 ± 7983725 ± 2113913 ± 4207112 ± 6245824 ± 727781 ± 364
/2396 ± 4382220 ± 2152330 ± 261

< 0.05 as compared to initial values.
< 0.05 as compared to the controls.
< 0.05 as compared to p/t day 14.