Matrix Metalloproteinase 9 Secreted by Hypoxia Cardiac Fibroblasts Triggers Cardiac Stem Cell Migration In Vitro

Figure 3

Supernatant of hypoxia induced CFs promoted CSCs migration. (a) shows CFs were exposed as control under normoxia while (b) (12 h), (c) (24 h), and (d) (48 h) demonstrate that CFs were cultured under different time period of hypoxia. (e) reveals the migration curve under different periods of hypoxia that peaks at 24 h. (f) denotes CSCs migration accounts in the well are counted according to the fixed location. indicates compared to the 0 h group. indicates compared to the 0 h group. ## indicates compared to the 24 h group.

(a) Hypoxia 0 h

(b) Hypoxia 12 h

(c) Hypoxia 24 h

(d) Hypoxia 48 h

(e) Migration trend

(f) Schematic view