Study on the Dynamic Biological Characteristics of Sca-1⁺ Hematopoietic Stem and Progenitor Cell Senescence

Figure 2

The superoxide damage and the antisuperoxide ability of Sca-1⁺ HSPCs by aging. (a) The activities of SOD of each sample (U/g, , ). (b) Glutathione contents in each group (µM, , ). (c) The absorbance value of each group which is proportional to superoxide (OD, , ). (d) MDA contents of Sca-1⁺ HSPCs in each group (nmol/mg, , ). Group A: 3-4-week-old mice, 13–16 g in body weight. Group B: 8-9-week-old mice, 20–25 g in body weight. Group C: 6-month-old mice, 35–40 g in body weight. Group D: 12-month-old mice, 39–43 g in body weight. Group E: 18-month-old mice, 37–45 g in body weight. (a–d) represent a significant difference of these columns ().

(a)

(b)

(c)

(d)