Stem Cells International

Research Article

Dexamethasone Regulates EphA5, a Potential Inhibitory Factor with Osteogenic Capability of Human Bone Marrow Stromal Cells

Table 2

Genes upregulated in hBMSCs by DEX treatment. Human genes upregulated by at least threefold in hBMSCs treated with DEX for 6 h at P5 compared with nontreated cells.
Genes　Gene bankLog2 ratio
FKBP5FK506 binding protein 5 NM_0041173.932
CYP19A1Cytochrome P450, family 19, subfamily A, polypeptide 1, transcript variant 2NM_0312263.880
HEYLHairy/enhancer-of-split related to YRPW motif-likeNM_0145713.162
BMP6Bone morphogenetic protein 6NM_0017183.006
DKK1Dickkopf homolog 1 (Xenopus laevis) NM_0122422.889
TNFAIP8L3Tumor necrosis factor, alpha-induced protein 8-like 3NM_2073812.685
INHBBInhibin, beta B NM_0021932.653
MYPNMyopalladin NM_0325782.594
CPMCarboxypeptidase M, transcript variant 1NM_0018742.590
XIRP1Xin actin-binding repeat containing 1NM_1942932.543
FOXO1Forkhead box O1NM_0020152.413
CDH15Cadherin 15, type 1, M-cadherin (myotubule)NM_0049332.377
GALGalanin prepropeptide NM_0159732.345
SNCAIPSynuclein, alpha interacting proteinNM_0054602.338
RNF128Ring finger protein 128, transcript variant 1NM_1944632.293
PRICKLE2Prickle homolog 2 (Drosophila) NM_1988592.289
ADRA1BAdrenergic, alpha-1B-, receptor NM_0006792.267
PTGER2Prostaglandin E receptor 2 (subtype EP2), 53 kDa NM_0009562.254
PPP1R14CProtein phosphatase 1, regulatory (inhibitor) subunit 14CNM_0309492.234
WISP1WNT1 inducible signaling pathway protein 1, transcript variant 2NM_0808382.220
ANGPTL4Angiopoietin-like 4, transcript variant 1NM_1393142.201
DIRAS3DIRAS family, GTP-binding RAS-like 3 NM_0046752.173
ZNF469Zinc finger protein 469NM_0011274642.145
CRYGSCrystallin, gamma SNM_0175412.140
MT1MMetallothionein 1M NM_1768702.121
SHC4SHC (Src homology 2 domain containing) family, member 4NM_2033492.070
SGEFSrc homology 3 domain-containing guanine nucleotide exchange factorNM_0155952.046
TET3Tet oncogene family member 3NM_1449932.019
PAG1Phosphoprotein associated with glycosphingolipid microdomains 1NM_0184401.986
EEPD1Endonuclease/exonuclease/phosphatase family domain containing 1 NM_0306361.980
SLC20A1Solute carrier family 20 (phosphate transporter), member 1 NM_0054151.971
CMKLR1Chemokine-like receptor 1, transcript variant 1NM_0011423431.970
FABP5Fatty acid binding protein 5 (psoriasis-associated)NM_0014441.948
ABLIM3Actin binding LIM protein family, member 3 NM_0149451.944
SEC14L2SEC14-like 2 (S. cerevisiae), transcript variant 1NM_0124291.942
CAMK2N1Calcium/calmodulin-dependent protein kinase II inhibitor 1 NM_0185841.906
HS3ST3B1Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 NM_0060411.839
KBTBD11Kelch repeat and BTB (POZ) domain containing 11 NM_0148671.829
WNT5BWingless-type MMTV integration site family, member 5B, transcript variant 2NM_0307751.817
SLASrc-like adaptor, transcript variant 1NM_0010455561.788
MT1GMetallothionein 1GNM_0059501.781
MT1AMetallothionein 1ANM_0059461.780
TOP1Topoisomerase (DNA) INM_0032861.771
MTSS1Metastasis suppressor 1NM_0147511.765
BAIAP2BAI1-associated protein 2, transcript variant 3NM_0063401.750
IRAK3Interleukin-1 receptor-associated kinase 3, transcript variant 1NM_0071991.740
MT1BMetallothionein 1BNM_0059471.734
FADS1Fatty acid desaturase 1NM_0134021.725
ABTB2Ankyrin repeat and BTB (POZ) domain containing 2NM_1458041.715
JARID2Jumonji, AT rich interactive domain 2NM_0049731.686
ITGA5Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) NM_0022051.652
MT1XMetallothionein 1X NM_0059521.647
GJB3Gap junction protein, beta 3, 31 kDa, transcript variant 1NM_0240091.645
MT1HMetallothionein 1H NM_0059511.639
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3NM_0245031.619
TCF7 Transcription factor 7 (T-cell specific, HMG-box), transcript variant 1NM_0032021.617
NR2F1Nuclear receptor subfamily 2, group F, member 1NM_0056541.613
A total of 28,780 human genes consistent with the quality criteria, genes upregulated threefold or higher are listed.