Whole-Genome Expression Analysis and Signal Pathway Screening of Synovium-Derived Mesenchymal Stromal Cells in Rheumatoid Arthritis

Figure 3

Scatter plot and volcano plots of differentially expressed genes. (a) Differentially expressed genes of SMSCs from both RA patients and HDs are shown in the scatter plot; each value represents a normalized signal value from each gene (log₂ scale). Fold-change lines are shown as green lines in the scatter plot, and gene fold-changes ≥ 2.0 between the RA and HD groups are shown above the top green line and below the bottom green line. (b) The volcano plots were constructed using fold-change values (log₂ scale) and values (−log₁₀ scale). The vertical lines correspond to 2.0-fold change up and down and the horizontal line represents a value of 0.05. The red point in the plot represents the significantly differentially expressed genes.

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