Whole-Genome Expression Analysis and Signal Pathway Screening of Synovium-Derived Mesenchymal Stromal Cells in Rheumatoid Arthritis

Table 3

GO analysis of RA SMSCs with different biological processes related to differentially expressed genes.

GO ID	Term	Regulation	Number of genes	Percentage of total gene number	Fold enrichment	value
GO:0009987	Cellular process	Up	1359	43.60%	1.078949506
GO:0008152	Metabolic process	Up	1028	32.98%	1.127180781
GO:0044238	Primary metabolic process	up	963	30.90%	1.163226478
GO:0044237	Cellular metabolic process	Up	941	30.19%	1.157274694
GO:0065007	Biological regulation	Up	920	29.52%	1.134286715
GO:0050789	Regulation of biological process	Up	862	27.65%	1.130113501
GO:0050794	Regulation of cellular process	Up	821	26.34%	1.133035445
GO:0043170	Cellular macromolecule metabolic process	Up	718	23.03%	1.162237783
GO:0050896	Response to stimulus	Up	708	22.71%	1.108798503
GO:0006807	Nitrogen compound metabolic process	Up	568	18.22%	1.063792239	0.028072195
GO:0009987	Cellular process	Down	584	34.13%	1.030034922	0.031637828
GO:0065007	Biological regulation	Down	403	23.55%	1.103818079	0.001406004
GO:0050789	Regulation of biological process	Down	372	21.74%	1.083465722	0.012748648
GO:0050896	Response to stimulus	Down	326	19.05%	1.134212455	0.001202522
GO:0032501	Multicellular organismal process	Down	259	15.14%	1.094089824	0.036294594
GO:0051716	Cellular response to stimulus	Down	237	13.85%	1.208258943	0.000275304
GO:0023052	Signaling	Down	209	12.22%	1.142323863	0.012379382
GO:0071840	Cellular component organization or biogenesis	Down	201	11.75%	1.275102033
GO:0032502	Developmental process	Down	200	11.69%	1.192861477	0.002106076
GO:0016043	Cellular component organization	Down	198	11.57%	1.295981777