Whole-Genome Expression Analysis and Signal Pathway Screening of Synovium-Derived Mesenchymal Stromal Cells in Rheumatoid Arthritis

Table 4

GO analysis of RA SMSCs with different cellular components related to differentially expressed genes.

GO ID	Term	Regulation	Number of genes	Percentage of total gene number	Fold enrichment	value
GO:0005623	Cell	Up	1531	49.12%	1.027156657
GO:0005622	Intracellular	Up	1296	41.58%	1.143609988
GO:0043229	Intracellular organelle	Up	1051	33.72%	1.120831397
GO:0005737	Cytoplasm	Up	1014	32.53%	1.277346130
GO:0043231	Intracellular membrane-bounded organelle	Up	968	31.06%	1.147230634
GO:0044444	Cytoplasmic part	Up	745	23.90%	1.315817744
GO:0044446	Intracellular organelle part	Up	607	19.47%	1.163042085
GO:0005634	Nucleus	Up	565	18.13%	1.073142161	0.017245693
GO:0032991	Macromolecular complex	Up	361	11.58%	1.081921665	0.042183953
GO:0043234	Protein complex	Up	314	10.07%	1.127231548	0.008327837
GO:0032991	Macromolecular complex	Down	177	10.34%	1.18550075	0.006000202
GO:0043232	Intracellular non-membrane-bounded organelle	Down	174	10.17%	1.521121372
GO:0043234	Protein complex	Down	157	9.18%	1.259572268	0.000893262
GO:0005856	Cytoskeleton	Down	127	7.42%	1.939965930
GO:0044459	Plasma membrane part	Down	112	6.55%	1.210497238	0.017123710
GO:0005829	Cytosol	Down	104	6.08%	1.201689499	0.025595975
GO:0005887	Integral to plasma membrane	Down	70	4.09%	1.334366755	0.007950984
GO:0031226	Intrinsic to plasma membrane	Down	70	4.09%	1.309313339	0.011994087
GO:0015630	Microtubule cytoskeleton	Down	61	3.57%	2.133880899
GO:0005694	Chromosome	Down	41	2.40%	1.75267224	0.000358288