Research Article
TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis
Figure 5
Fibrogenic markers of transplanted HPCs, HPCs pretreated with TGF-β1 for 12 h, and HPCs pretreated with TGF-β1 for 48 h on recovery in the rat model with CCl4-induced injury. The expression of α-SMA in liver tissues was detected by immunohistochemistry (a) and western blot (b). The expression levels of collagen-1 in liver tissues were measured by an enzyme-linked immunosorbent assay (c). ALT (d) and ALB (e) in the blood samples collected at the end of the experiment were analyzed. All data are expressed as the mean ± SD from three independent experiments.
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