TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis

Table 1

Quantitative evaluation of liver fibrosis.

Group	Number of rats	Liver fibrosis stage							Average stage
		S0	S1	S2	S3	S4	S5	S6
PBS	4	0	0	0	1	2	1	0	4.0 ± 0.4
HPCs	6	0	0	3	3	0	0	0	2.7 ± 0.2
HPCs pretreated with TGF-1 for 12 h	6	0	4	2	0	0	0	0	1.7 ± 0.2
HPCs pretreated with TGF-1 for 48 h	6	0	0	0	0	1	3	2	5.2 ± 0.3

The average scores are expressed as mean ± standard deviation (SD) in arbitrary units. indicates , compared to the group of PBS group. # indicates P < 0.05, compared to the group of HPCs group. indicates , compared to the group of HPCs pretreated with TGF-1 for 12 h.