Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy

<div>Characteristics of MSCs derived from AF of normal and pathological gestation during cultivation. (a) Representative images of initially spindle-shaped MSCs morphology in early (p3) and senescent passages (p7-8) with a 40x magnification are presented. (b) Differential proliferation of MSCs from AF of individual donors (D) during cultivation to passage 8. (c) Senescence-associated <i>β</i>-galactosidase staining in the late passage (p7-8); NS: nonstained cells. Representative results of four independent MSC preparations are demonstrated.</div>

Stem Cells International

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Figure 1

Figure 1: Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy 

Figure 1 | Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy 