Mesenchymal Stem Cells Derived from Human Exocrine Pancreas Spontaneously Express Pancreas Progenitor-Cell Markers in a Cell-Passage-Dependent Manner

Figure 5

Quantitative analysis of mRNA expression of key pancreatic transcription factors in hpMSCs. Analysis of key pancreatic transcription factors Pdx1, Ngn3, and MafA expression in human islet cells, human ASCs, and hpMSCs by qPCR. Reference expression levels (1-fold) were calculated relative to baseline expression levels measured in hASCs. (a) Pdx1 was highly expressed in islet cells () and hpMSCs (), whereas (b) Ngn3 was expressed in both islet cells () and hpMSCs () at comparable levels. (c) MafA was expressed at higher levels in hpMSCs () than in islet cells (). Error bars indicate SD (); ; .

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